Adamts4 | ADAM metallopeptidase with thrombospondin type 1 motif 4

GeneMGI:1339949Synonyms: ADAM-TS4, aggrecanase-1

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Skeleton

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased grip strength	1 supporting dataset	Adamts4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.04x10^-5
abnormal bone structure	1 supporting dataset	Adamts4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.15x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adamts4.

Associated images

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Histopathology

There is no histopathology data found for Adamts4.

IMPC related publications

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External links

No external links available for Adamts4.

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*Adamts4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Adamts4^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Adamts4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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