Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)

GeneMGI:1339759Synonyms: beta c, AIC2B, +7 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Vision/eye Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased eosinophil cell number	1 supporting dataset	Csf2rb^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	7.31x10^-10
abnormal behavior	1 supporting dataset	Csf2rb^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	1.97x10^-5
decreased anxiety-related response	1 supporting dataset	Csf2rb^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	3.74x10^-5
abnormal eye anterior chamber depth	1 supporting dataset	Csf2rb^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	1.08x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Csf2rb^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased thigmotaxis	2 supporting datasets	Csf2rb^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	1.97x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Csf2rb.

Associated images

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Histopathology

There is no histopathology data found for Csf2rb.

IMPC related publications

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External links

No external links available for Csf2rb.

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*Csf2rb^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Csf2rb^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Csf2rb^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Csf2rb^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Csf2rb^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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