Myh8 | myosin, heavy polypeptide 8, skeletal muscle, perinatal
Physiological systems
21 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Hematopoietic system Skeleton Mortality/aging Renal/urinary system
14 No significant impact
3 Not tested
Data collections
Gene metrics:6Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
preweaning lethality, complete penetrance | 3 supporting datasets | Myh8em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
edema | 1 supporting dataset | Myh8em1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
abnormal sternum morphology | 1 supporting dataset | Myh8em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
abnormal embryo size | 1 supporting dataset | Myh8em1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
decreased hematocrit | 1 supporting dataset | Myh8em1(IMPC)Tcp | heterozygote | Early adult | 2.35x10-7 | ||
enlarged urinary bladder | 1 supporting dataset | Myh8em1(IMPC)Tcp | heterozygote | Early adult | N/A * |
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External links
No external links available for Myh8.
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Myh8em1(IMPC)Tcp | Exon Deletion | | mouse |
Myh8tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Myh8tm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |
Myh8tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
Myh8tm2(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Myh8tm2e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |