S100a6 | S100 calcium binding protein A6 (calcyclin)
Physiological systems
22 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Mortality/aging
19 No significant impact
2 Not tested
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
58Embryo tissues
increased vertical activity | 1 supporting dataset | S100a6tm1b(KOMP)Wtsi | heterozygote | Early adult | 5.59x10-5 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | S100a6tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
preweaning lethality, incomplete penetrance | 2 supporting datasets | S100a6tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
increased respiratory quotient | 1 supporting dataset | S100a6tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.23x10-8 |
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External links
No external links available for S100a6.
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S100a6tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
S100a6tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
S100a6tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |