S1pr3 | sphingosine-1-phosphate receptor 3

GeneMGI:1339365Synonyms: LPb3, Edg3, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Reproductive system Integument Vision/eye Cardiovascular system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin coloration1 supporting datasetS1pr3tm1b(EUCOMM)WtsihomozygoteEarly adult7.22x10-8 
male infertility1 supporting datasetS1pr3tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetS1pr3tm1b(EUCOMM)WtsihomozygoteEarly adult4.85x10-7 
female infertility1 supporting datasetS1pr3tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal retina blood vessel morphology1 supporting datasetS1pr3tm1b(EUCOMM)WtsihomozygoteEarly adult2.14x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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S1pr3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
S1pr3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
S1pr3tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
S1pr3tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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