S100a1 | S100 calcium binding protein A1

GeneMGI:1338917Synonyms: S100a, S100

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Hearing/vestibular/ear Vision/eye

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetS100a1em1(IMPC)MbphomozygoteEarly adult3.77x10-6 
abnormal auditory brainstem response1 supporting datasetS100a1em1(IMPC)MbphomozygoteEarly adult5.64x10-5 
abnormal vitreous body morphology1 supporting datasetS100a1em1(IMPC)MbphomozygoteEarly adult9.49x10-7 
abnormal eye morphology1 supporting datasetS100a1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetS100a1em1(IMPC)MbphomozygoteEarly adultN/A * 
anophthalmia1 supporting datasetS100a1em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged testis1 supporting datasetS100a1em1(IMPC)MbphomozygoteEarly adultN/A * 
small testis1 supporting datasetS100a1em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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S100a1em1(IMPC)MbpInter-exon deletionmouse
S100a1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
S100a1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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