Padi4 | peptidyl arginine deiminase, type IV

GeneMGI:1338898Synonyms: Pdi4, PAD type IV, +1 more

Physiological systems

20 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Cardiovascular system Renal/urinary system

10 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal liver morphology	1 supporting dataset	Padi4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Padi4^em1(IMPC)Mbp	homozygote	Late adult	6.6x10^-5
enlarged heart	1 supporting dataset	Padi4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Padi4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged spleen	2 supporting datasets	Padi4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Padi4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Padi4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Padi4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Padi4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Padi4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Padi4.

Associated images

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Histopathology

There is no histopathology data found for Padi4.

IMPC related publications

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External links

No external links available for Padi4.

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*Padi4^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Padi4^{tm560(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Padi4^{tm560(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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