St14 | suppression of tumorigenicity 14 (colon carcinoma)

GeneMGI:1338881Synonyms: Tmprss14, MT-SP1, +3 more

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Integument Embryo Growth/size/body region Limbs/digits/tail Vision/eye Liver/biliary system Mortality/aging

15 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

51Embryo tissues

Phenotypes

Phy. System:

Life Stage:



pale yolk sac	1 supporting dataset	St14^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal limb bud morphology	1 supporting dataset	St14^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
pale liver	1 supporting dataset	St14^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal liver size	1 supporting dataset	St14^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal placenta size	1 supporting dataset	St14^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal eye morphology	1 supporting dataset	St14^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal embryo size	1 supporting dataset	St14^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	St14^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
prenatal lethality prior to heart atrial septation	1 supporting dataset	St14^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
pallor	1 supporting dataset	St14^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for St14.

Associated images

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Histopathology

There is no histopathology data found for St14.

IMPC related publications

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External links

No external links available for St14.

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*St14^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*St14^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*St14^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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