Maz | MYC-associated zinc finger protein (purine-binding transcription factor)

GeneMGI:1338823Synonyms: PUR1, Pur-1, +2 more

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Growth/size/body region Hearing/vestibular/ear Behavior/neurological

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal head morphology1 supporting datasetMazem1(IMPC)IcsheterozygoteEarly adult5.28x10-5 
abnormal auditory brainstem response1 supporting datasetMazem1(IMPC)IcsheterozygoteEarly adult3.66x10-5 
decreased exploration in new environment1 supporting datasetMazem1(IMPC)IcsheterozygoteEarly adult7.54x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mazem1(IMPC)IcsExon Deletionmouse
Maztm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Maztm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell

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