Ikbkb | inhibitor of kappaB kinase beta

GeneMGI:1338071Synonyms: IKK2, IKKbeta, +3 more

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

3Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes



preweaning lethality, incomplete penetrance	2 supporting datasets		Ikbkb^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult		N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ikbkb.

Associated images

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Histopathology

There is no histopathology data found for Ikbkb.

IMPC related publications

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External links

No external links available for Ikbkb.

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*Ikbkb^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ikbkb^{tm39952(L1L2_gt0_Del_LacZ)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Ikbkb^{tm39952(pL1L2_GT0_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Ikbkb^{tm39952(pL1L2_frt15_BetactinBSD_frt14_neo_Rox)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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