Itsn2 | intersectin 2

GeneMGI:1338049Synonyms: Sh3d1B, Eh domain, SH3 domain regulator of endocytosis 2, +2 more

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Integument Behavior/neurological

19 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hyperactivity	4 supporting datasets	Itsn2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.85x10^-6
abnormal coat/ hair morphology	1 supporting dataset	Itsn2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.96x10^-6
increased exploration in new environment	1 supporting dataset	Itsn2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	8.32x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Itsn2.

Associated images

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Histopathology

There is no histopathology data found for Itsn2.

IMPC related publications

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External links

No external links available for Itsn2.

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*Itsn2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Itsn2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Itsn2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Itsn2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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