Bex2 | brain expressed X-linked 2

GeneMGI:1338017Synonyms: Bex1

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Pigmentation Immune system Integument Nervous system Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:87Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased locomotor activity	4 supporting datasets	Bex2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.6x10^-6
decreased locomotor activity	4 supporting datasets	Bex2^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	1.71x10^-7
abnormal coat/hair pigmentation	3 supporting datasets	Bex2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.34x10^-7
abnormal lens morphology	2 supporting datasets	Bex2^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	2.13x10^-9
increased startle reflex	1 supporting dataset	Bex2^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	1.27x10^-8
decreased red blood cell distribution width	1 supporting dataset	Bex2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.31x10^-5
increased leukocyte cell number	1 supporting dataset	Bex2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.95x10^-5
decreased prepulse inhibition	1 supporting dataset	Bex2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.93x10^-5
increased startle reflex	1 supporting dataset	Bex2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.74x10^-5
abnormal retina morphology	1 supporting dataset	Bex2^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	1.31x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bex2.

Associated images

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Histopathology

There is no histopathology data found for Bex2.

IMPC related publications

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External links

No external links available for Bex2.

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*Bex2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Bex2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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