Auh | AU RNA binding protein/enoyl-coenzyme A hydratase

GeneMGI:1338011Synonyms: W91705

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased eosinophil cell number1 supporting datasetAuhem1(IMPC)TcphomozygoteEarly adult2.01x10-7 
increased circulating alanine transaminase level1 supporting datasetAuhem1(IMPC)TcphomozygoteEarly adult2.51x10-6 
abnormal sternum morphology1 supporting datasetAuhem1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Auhem1(IMPC)TcpInter-exon deletionmouse
Auhtm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Auhtm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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