Gdap2 | ganglioside-induced differentiation-associated-protein 2

GeneMGI:1338001Synonyms: D3Ertd801e

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating fructosamine level1 supporting datasetGdap2em1(IMPC)WtsihomozygoteEarly adult1.32x10-8 
decreased circulating amylase level1 supporting datasetGdap2em1(IMPC)WtsihomozygoteEarly adult1.85x10-5 
increased bone mineral density1 supporting datasetGdap2em1(IMPC)WtsihomozygoteEarly adult6.97x10-5 
absent pinna reflex1 supporting datasetGdap2em1(IMPC)WtsihomozygoteEarly adult1.99x10-5 
decreased total body fat amount1 supporting datasetGdap2em1(IMPC)WtsihomozygoteEarly adult1.68x10-7 
decreased circulating serum albumin level1 supporting datasetGdap2em1(IMPC)WtsihomozygoteEarly adult4.01x10-9 
increased lean body mass1 supporting datasetGdap2em1(IMPC)WtsihomozygoteEarly adult4.29x10-6 
thrombocytosis1 supporting datasetGdap2em1(IMPC)WtsihomozygoteEarly adult6.82x10-6 
decreased circulating thyroxine level1 supporting datasetGdap2em1(IMPC)WtsihomozygoteEarly adult4.52x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gdap2em1(IMPC)WtsiDeletionmouse
Gdap2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Gdap2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Gdap2tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Gdap2tm2e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Gdap2tm3e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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