Slc7a7 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 7

GeneMGI:1337120Synonyms: my+lat1

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Embryo Growth/size/body region Mortality/aging

18 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues

Phenotypes

preweaning lethality, complete penetrance6 supporting datasetsSlc7a7em1(IMPC)BayhomozygoteEarly adultN/A * 
abnormal placenta size1 supporting datasetSlc7a7em1(IMPC)BayhomozygoteE18.5N/A * 
abnormal embryo size2 supporting datasetsSlc7a7em1(IMPC)BayhomozygoteE18.5N/A * 
increased lean body mass1 supporting datasetSlc7a7em1(IMPC)BayheterozygoteEarly adult3.41x10-5 
embryonic growth retardation1 supporting datasetSlc7a7em1(IMPC)BayhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc7a7em1(IMPC)BayExon Deletionmouse
Slc7a7tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Slc7a7tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)mouse
Slc7a7tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Slc7a7tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Slc7a7tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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