Ap3s1 | adaptor-related protein complex 3, sigma 1 subunit

GeneMGI:1337062Synonyms: [s]3A

Physiological systems

16 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

15 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes



increased circulating alkaline phosphatase level	1 supporting dataset	Ap3s1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.01x10^-6
increased fasting circulating glucose level	1 supporting dataset	Ap3s1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.7x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ap3s1.

Associated images

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Histopathology

There is no histopathology data found for Ap3s1.

IMPC related publications

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External links

No external links available for Ap3s1.

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*Ap3s1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ap3s1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ap3s1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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