Ap3s2 | adaptor-related protein complex 3, sigma 2 subunit
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological
18 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| hyperactivity | 3 supporting datasets | Ap3s2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.28x10-5 | ||
| abnormal behavior | 1 supporting dataset | Ap3s2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.65x10-7 | ||
| decreased thigmotaxis | 2 supporting datasets | Ap3s2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.65x10-7 | ||
| decreased circulating fructosamine level | 1 supporting dataset | Ap3s2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.31x10-6 | ||
| decreased locomotor activity | 1 supporting dataset | Ap3s2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.26x10-7 | ||
| decreased anxiety-related response | 1 supporting dataset | Ap3s2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.47x10-6 |
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External links
No external links available for Ap3s2.
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| Ap3s2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Ap3s2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ap3s2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |