Hapln1 | hyaluronan and proteoglycan link protein 1

GeneMGI:1337006Synonyms: CLP, cartilage linking protein 1, +4 more

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

19 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



impaired righting response	1 supporting dataset	Hapln1^{tm1.1(KOMP)Mbp}	heterozygote	Early adult	1.76x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Hapln1^{tm1.1(KOMP)Mbp}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hapln1.

Associated images

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Histopathology

There is no histopathology data found for Hapln1.

IMPC related publications

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External links

No external links available for Hapln1.

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*Hapln1^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Hapln1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Hapln1^{tm1.1(KOMP)Mbp}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Hapln1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes