Slc6a20b | solute carrier family 6 (neurotransmitter transporter), member 20B

GeneMGI:1336891Synonyms: Slc6a20, Xtrp3, +2 more

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased blood urea nitrogen level1 supporting datasetSlc6a20bem1(IMPC)JhomozygoteEarly adult3.52x10-5 
abnormal coat/ hair morphology1 supporting datasetSlc6a20bem1(IMPC)JhomozygoteEarly adult1.57x10-5 
cornea deposits1 supporting datasetSlc6a20bem1(IMPC)JhomozygoteEarly adult4.81x10-5 
increased mean corpuscular hemoglobin1 supporting datasetSlc6a20bem1(IMPC)JhomozygoteEarly adult9.97x10-5 
increased circulating bilirubin level1 supporting datasetSlc6a20bem1(IMPC)JhomozygoteEarly adult2.4x10-5 
increased heart weight1 supporting datasetSlc6a20bem1(IMPC)JhomozygoteEarly adult6.89x10-7 
persistence of hyaloid vascular system1 supporting datasetSlc6a20bem1(IMPC)JhomozygoteEarly adult4.88x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc6a20bem1(IMPC)JExon Deletionmouse
Slc6a20btm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Slc6a20btm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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