Fkbp1b | FK506 binding protein 1b

GeneMGI:1336205Synonyms: FKBP12.6, 12.6kDa, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Vision/eye Behavior/neurological Cardiovascular system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina blood vessel morphology	1 supporting dataset	Fkbp1b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.03x10^-6
increased startle reflex	1 supporting dataset	Fkbp1b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.59x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fkbp1b.

Associated images

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Histopathology

There is no histopathology data found for Fkbp1b.

IMPC related publications

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External links

No external links available for Fkbp1b.

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*Fkbp1b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fkbp1b^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Fkbp1b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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