Prkab2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit

GeneMGI:1336185Synonyms: 5730553K21Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hematopoietic system Mortality/aging

15 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

increased eosinophil cell number2 supporting datasetsPrkab2tm1b(EUCOMM)HmguheterozygoteEarly adult1.17x10-6 
preweaning lethality, incomplete penetrance1 supporting datasetPrkab2tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
decreased mean platelet volume1 supporting datasetPrkab2tm1b(EUCOMM)HmguheterozygoteEarly adult9.27x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Prkab2tm1(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
Prkab2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Prkab2tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Prkab2tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter