Gng12 | guanine nucleotide binding protein (G protein), gamma 12

GeneMGI:1336171Synonyms: 2010305F15Rik

Physiological systems

15 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological Cardiovascular system

11 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



abnormal retina vasculature morphology	1 supporting dataset	Gng12^em1(IMPC)Tcp	homozygote	Early adult	1.7x10^-8
decreased circulating phosphate level	1 supporting dataset	Gng12^em1(IMPC)J	homozygote	Early adult	5.24x10^-5
increased grip strength	1 supporting dataset	Gng12^em1(IMPC)J	homozygote	Early adult	7.71x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Gng12^em1(IMPC)Tcp	homozygote	Early adult	1.44x10^-8
abnormal lens morphology	1 supporting dataset	Gng12^em1(IMPC)Tcp	homozygote	Early adult	1.41x10^-5
increased circulating calcium level	1 supporting dataset	Gng12^em1(IMPC)J	homozygote	Early adult	2.69x10^-26
cataract	1 supporting dataset	Gng12^em1(IMPC)Tcp	homozygote	Early adult	1.42x10^-5
anophthalmia	1 supporting dataset	Gng12^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased startle reflex	1 supporting dataset	Gng12^em1(IMPC)J	homozygote	Early adult	8.51x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Gng12.

Associated images

Loading...

Histopathology

There is no histopathology data found for Gng12.

IMPC related publications

Loading...

External links

No external links available for Gng12.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Gng12^em1(IMPC)J*	Exon Deletion	‌	mouse
*Gng12^em1(IMPC)Tcp*	Inter-exon deletion	‌	mouse
*Gng12^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gng12^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes