Uap1 | UDP-N-acetylglucosamine pyrophosphorylase 1

GeneMGI:1334459Synonyms: SPAG2, AGX1, +2 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal lens morphology	1 supporting dataset	Uap1^em1(IMPC)Tcp	heterozygote	Early adult	1.62x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Uap1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Uap1^em1(IMPC)Tcp	heterozygote	Early adult	2.5x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Uap1^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Uap1.

Associated images

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Histopathology

There is no histopathology data found for Uap1.

IMPC related publications

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External links

No external links available for Uap1.

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*Uap1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Uap1^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Uap1^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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