Aspm | abnormal spindle microtubule assembly

GeneMGI:1334448Synonyms: D330028K02Rik, MCPH5, +3 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased total body fat amount	1 supporting dataset	Aspm^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.78x10^-5
decreased lean body mass	1 supporting dataset	Aspm^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.1x10^-5
increased circulating HDL cholesterol level	1 supporting dataset	Aspm^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.16x10^-6
increased circulating glycerol level	1 supporting dataset	Aspm^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.11x10^-5
thrombocytopenia	1 supporting dataset	Aspm^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.53x10^-6
increased circulating cholesterol level	1 supporting dataset	Aspm^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.03x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Aspm.

Associated images

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Histopathology

There is no histopathology data found for Aspm.

IMPC related publications

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External links

No external links available for Aspm.

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*Aspm^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Aspm^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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