Ppp1r17 | protein phosphatase 1, regulatory subunit 17

GeneMGI:1333876Synonyms: G-substrate, Gsbs

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased neutrophil cell number1 supporting datasetPpp1r17em1(IMPC)HhomozygoteEarly adult7.92x10-5 
decreased circulating alkaline phosphatase level1 supporting datasetPpp1r17em1(IMPC)HhomozygoteEarly adult9.86x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ppp1r17em1(IMPC)HIndelmouse
Ppp1r17em2(IMPC)HIndelmouse
Ppp1r17tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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