Ate1 | arginyltransferase 1

Physiological systems

23 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Embryo Growth/size/body region Cardiovascular system Mortality/aging

17 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged heart1 supporting datasetAte1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal embryo size1 supporting datasetAte1em1(IMPC)CcpczhomozygoteE9.5N/A * 
abnormal seminal vesicle morphology1 supporting datasetAte1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetAte1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetAte1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetAte1em1(IMPC)CcpczhomozygoteE12.5N/A * 
abnormal pancreas morphology1 supporting datasetAte1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ate1em1(IMPC)CcpczExon Deletionmouse
Ate1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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