Arhgap31 | Rho GTPase activating protein 31

GeneMGI:1333857Synonyms: CdGAP

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Nervous system Mortality/aging Cardiovascular system

15 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal embryo size1 supporting datasetArhgap31em1(IMPC)BayheterozygoteE18.5N/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsArhgap31em1(IMPC)BayhomozygoteEarly adultN/A * 
decreased prepulse inhibition3 supporting datasetsArhgap31em1(IMPC)BayheterozygoteEarly adult2.53x10-10 
hemorrhage1 supporting datasetArhgap31em1(IMPC)BayhomozygoteE15.5N/A * 
edema1 supporting datasetArhgap31em1(IMPC)BayhomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Arhgap31em1(IMPC)BayExon Deletionmouse
Arhgap31tm1(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Arhgap31tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Arhgap31tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Arhgap31tm41948(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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