Slc22a3 | solute carrier family 22 (organic cation transporter), member 3
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Vision/eye Behavior/neurological
18 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
anophthalmia | 1 supporting dataset | Slc22a3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
hyperactivity | 1 supporting dataset | Slc22a3em1(IMPC)Mbp | homozygote | Early adult | 3.15x10-5 | ||
decreased thigmotaxis | 2 supporting datasets | Slc22a3em1(IMPC)Mbp | homozygote | Early adult | 6.64x10-7 | ||
decreased anxiety-related response | 1 supporting dataset | Slc22a3em1(IMPC)Mbp | homozygote | Early adult | 9.46x10-7 | ||
decreased locomotor activity | 1 supporting dataset | Slc22a3em1(IMPC)Mbp | homozygote | Early adult | 6.23x10-7 | ||
abnormal eye morphology | 1 supporting dataset | Slc22a3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
abnormal behavior | 1 supporting dataset | Slc22a3em1(IMPC)Mbp | homozygote | Early adult | 7.31x10-7 |
| | | | | | | | | |
External links
No external links available for Slc22a3.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Slc22a3em1(IMPC)Mbp | Exon Deletion | | mouse |
Slc22a3tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Slc22a3tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
Slc22a3tm88441(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |