Mbd1 | methyl-CpG binding domain protein 1

GeneMGI:1333811Synonyms: Cxxc3, PCM1

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Reproductive system Hematopoietic system Skeleton

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



vertebral transformation	1 supporting dataset	Mbd1^{em1(IMPC)Wtsi}	homozygote	Early adult	3.11x10^-6
female infertility	1 supporting dataset	Mbd1^{em1(IMPC)Wtsi}	homozygote	Early adult	N/A ^*
lordosis	1 supporting dataset	Mbd1^{em1(IMPC)Wtsi}	homozygote	Early adult	1.9x10^-5
increased mean corpuscular hemoglobin	1 supporting dataset	Mbd1^{em1(IMPC)Wtsi}	homozygote	Early adult	1.79x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mbd1.

Associated images

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Histopathology

There is no histopathology data found for Mbd1.

IMPC related publications

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External links

No external links available for Mbd1.

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*Mbd1^{em1(IMPC)Wtsi}*	Deletion	‌	mouse
*Mbd1^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Mbd1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Mbd1^{tm437424(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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