Klf12 | Kruppel-like transcription factor 12

GeneMGI:1333796Synonyms: 2700063E05Rik, B130052C06Rik, +2 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina inner nuclear layer morphology	1 supporting dataset	Klf12^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.99x10^-5
decreased circulating serum albumin level	1 supporting dataset	Klf12^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.36x10^-5
increased cornea thickness	1 supporting dataset	Klf12^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.88x10^-6
decreased circulating calcium level	1 supporting dataset	Klf12^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.47x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Klf12.

Associated images

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Histopathology

There is no histopathology data found for Klf12.

IMPC related publications

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External links

No external links available for Klf12.

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*Klf12^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Klf12^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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