Srp72 | signal recognition particle 72

GeneMGI:1333795Synonyms: 72kDa, 5730576P14Rik

Physiological systems

15 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

13 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased thigmotaxis2 supporting datasetsSrp72em1(IMPC)BayheterozygoteEarly adult5.46x10-5 
preweaning lethality, complete penetrance2 supporting datasetsSrp72em1(IMPC)BayhomozygoteEarly adultN/A * 
hyperactivity1 supporting datasetSrp72em1(IMPC)BayheterozygoteEarly adult6.54x10-5 
abnormal behavior1 supporting datasetSrp72em1(IMPC)BayheterozygoteEarly adult5.46x10-5 
increased vertical activity1 supporting datasetSrp72em1(IMPC)BayheterozygoteEarly adult1.85x10-5 
decreased locomotor activity1 supporting datasetSrp72em1(IMPC)BayheterozygoteEarly adult1.37x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Srp72em1(IMPC)BayExon Deletionmouse
Srp72tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Srp72tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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