Car6 | carbonic anhydrase 6

GeneMGI:1333786Synonyms: DOC1

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Respiratory system Hematopoietic system Skeleton Craniofacial

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged spleen	1 supporting dataset	Car6^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal tooth color	1 supporting dataset	Car6^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Car6^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Car6^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Car6^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased lung elastance	1 supporting dataset	Car6^{em1(IMPC)Ccpcz}	homozygote	Early adult	8.5x10^-5
enlarged thymus	1 supporting dataset	Car6^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal retina morphology	1 supporting dataset	Car6^{em1(IMPC)Ccpcz}	homozygote	Early adult	8.25x10^-5
abnormal thymus morphology	1 supporting dataset	Car6^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Car6^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Car6.

Associated images

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Histopathology

There is no histopathology data found for Car6.

IMPC related publications

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External links

No external links available for Car6.

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*Car6^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Car6^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Car6^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Car6^{tm46959(L1L2_st1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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