Tfec | transcription factor EC

GeneMGI:1333760Synonyms: TFEC, bHLHe34, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Limbs/digits/tail

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal tail morphology	1 supporting dataset	Tfec^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.01x10^-8
increased circulating cholesterol level	1 supporting dataset	Tfec^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.7x10^-5
abnormal coat/hair pigmentation	1 supporting dataset	Tfec^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.15x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tfec.

Associated images

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Histopathology

There is no histopathology data found for Tfec.

IMPC related publications

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External links

No external links available for Tfec.

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*Tfec^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tfec^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tfec^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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