Pdcd6ip | programmed cell death 6 interacting protein

GeneMGI:1333753Synonyms: Alix, AIP1

Physiological systems

23 / 24 physiological systems tested

14 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Digestive/alimentary Hematopoietic system Cardiovascular system Renal/urinary system Homeostasis/metabolism Nervous system Vision/eye Respiratory system Behavior/neurological

9 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:33Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:

Life Stage:



enlarged lymph nodes	1 supporting dataset	Pdcd6ip^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal stomach morphology	1 supporting dataset	Pdcd6ip^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Pdcd6ip^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
increased blood urea nitrogen level	1 supporting dataset	Pdcd6ip^{em1(IMPC)Hmgu}	homozygote	Late adult	5.35x10^-6
decreased brain size	2 supporting datasets	Pdcd6ip^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal brain morphology	2 supporting datasets	Pdcd6ip^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
microphthalmia	1 supporting dataset	Pdcd6ip^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
small kidney	2 supporting datasets	Pdcd6ip^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
small testis	1 supporting dataset	Pdcd6ip^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal brain morphology	2 supporting datasets	Pdcd6ip^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pdcd6ip.

Associated images

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Histopathology

There is no histopathology data found for Pdcd6ip.

IMPC related publications

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External links

No external links available for Pdcd6ip.

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*Pdcd6ip^{em1(IMPC)Hmgu}*	Indel	‌	mouse
*Pdcd6ip^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Pdcd6ip^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Pdcd6ip^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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