Bcl7b | B cell CLL/lymphoma 7B
GeneMGI:1332238
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Growth/size/body region Vision/eye Behavior/neurological Cardiovascular system Mortality/aging
13 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues
| abnormal retina inner nuclear layer morphology | 2 supporting datasets | Bcl7btm1b(EUCOMM)Wtsi | homozygote | Early adult | 3.8x10-13 | ||
| decreased total retina thickness | 2 supporting datasets | Bcl7btm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.33x10-24 | ||
| increased grip strength | 1 supporting dataset | Bcl7btm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.02x10-5 | ||
| increased heart weight | 1 supporting dataset | Bcl7btm1b(EUCOMM)Wtsi | homozygote | Early adult | 7.48x10-6 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Bcl7btm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Bcl7b.
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| Bcl7btm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Bcl7btm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Bcl7btm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |