Atp8a1 | ATPase phospholipid transporting 8A1

GeneMGI:1330848Synonyms: Atp3a2, B230107D19Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased startle reflex	3 supporting datasets	Atp8a1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.08x10^-7
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Atp8a1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.51x10^-10
increased blood urea nitrogen level	1 supporting dataset	Atp8a1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.7x10^-6
increased lactate dehydrogenase level	1 supporting dataset	Atp8a1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.71x10^-6
decreased erythrocyte cell number	1 supporting dataset	Atp8a1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.33x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Atp8a1.

Associated images

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Histopathology

There is no histopathology data found for Atp8a1.

IMPC related publications

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External links

No external links available for Atp8a1.

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*Atp8a1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse

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