Arg2 | arginase type II

GeneMGI:1330806Synonyms: AII

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Growth/size/body region Hearing/vestibular/ear Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal heart morphology	2 supporting datasets	Arg2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Arg2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small spleen	1 supporting dataset	Arg2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal auditory brainstem response	1 supporting dataset	Arg2^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.59x10^-7
abnormal thymus morphology	1 supporting dataset	Arg2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Arg2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
kyphosis	1 supporting dataset	Arg2^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.36x10^-5
decreased exploration in new environment	1 supporting dataset	Arg2^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.59x10^-8
abnormal spine curvature	1 supporting dataset	Arg2^{em1(IMPC)Ccpcz}	homozygote	Early adult	7.43x10^-6
lordosis	1 supporting dataset	Arg2^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.49x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arg2.

Associated images

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Histopathology

There is no histopathology data found for Arg2.

IMPC related publications

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External links

No external links available for Arg2.

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*Arg2^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Arg2^{tm89576(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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