Rab33b | RAB33B, member RAS oncogene family

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Cardiovascular system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

prolonged PR interval1 supporting datasetRab33bem1(IMPC)JhomozygoteEarly adult9.31x10-8 
decreased circulating cholesterol level1 supporting datasetRab33bem1(IMPC)JhomozygoteEarly adult7.52x10-5 
increased circulating aspartate transaminase level1 supporting datasetRab33bem1(IMPC)JhomozygoteEarly adult1.2x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Rab33bem1(IMPC)JExon Deletionmouse
Rab33btm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rab33btm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Rab33btm46140(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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