Trpm1 | transient receptor potential cation channel, subfamily M, member 1

GeneMGI:1330305Synonyms: LTRPC1, melastatin, +2 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



impaired glucose tolerance	1 supporting dataset	Trpm1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.54x10^-7
increased circulating creatine kinase level	1 supporting dataset	Trpm1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.16x10^-5
mydriasis	1 supporting dataset	Trpm1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.57x10^-22
impaired pupillary reflex	1 supporting dataset	Trpm1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.57x10^-22
increased circulating HDL cholesterol level	1 supporting dataset	Trpm1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.93x10^-5
limb grasping	1 supporting dataset	Trpm1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.69x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Trpm1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Trpm1.

IMPC related publications

Loading...

External links

No external links available for Trpm1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Trpm1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Trpm1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes