Dpm1 | dolichyl-phosphate mannosyltransferase subunit 1, catalytic

GeneMGI:1330239

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased grip strength	1 supporting dataset	Dpm1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	8.46x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Dpm1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
prenatal lethality prior to heart atrial septation	1 supporting dataset	Dpm1^{tm1b(KOMP)Wtsi}	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dpm1.

Associated images

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Histopathology

There is no histopathology data found for Dpm1.

IMPC related publications

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External links

No external links available for Dpm1.

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*Dpm1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dpm1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dpm1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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