Mllt10 | myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10

GeneMGI:1329038Synonyms: B130021D15Rik, Af10, +1 more

Physiological systems

22 / 24 physiological systems tested

18 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Hearing/vestibular/ear Hematopoietic system Craniofacial Cardiovascular system Homeostasis/metabolism Embryo Limbs/digits/tail Nervous system Vision/eye Liver/biliary system Skeleton Mortality/aging

4 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:28Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Mllt10^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal liver morphology	2 supporting datasets	Mllt10^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Mllt10^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal ovary morphology	1 supporting dataset	Mllt10^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Mllt10^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
microphthalmia	1 supporting dataset	Mllt10^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal facial morphology	1 supporting dataset	Mllt10^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
enlarged spleen	1 supporting dataset	Mllt10^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Mllt10^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
facial cleft	1 supporting dataset	Mllt10^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Mllt10.

Associated images

Loading...

Histopathology

There is no histopathology data found for Mllt10.

IMPC related publications

Loading...

External links

No external links available for Mllt10.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Mllt10^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Mllt10^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mllt10^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Mllt10^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Mllt10^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes