Msh5 | mutS homolog 5

GeneMGI:1329021Synonyms: Mut5, G7

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Vision/eye Hematopoietic system Behavior/neurological Skeleton

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating unsaturated transferrin level	1 supporting dataset	Msh5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.57x10^-5
decreased bone mineral density	1 supporting dataset	Msh5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.51x10^-5
abnormal lens morphology	2 supporting datasets	Msh5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.2x10^-6
increased leukocyte cell number	1 supporting dataset	Msh5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.18x10^-7
increased startle reflex	1 supporting dataset	Msh5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.64x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Msh5.

Associated images

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Histopathology

There is no histopathology data found for Msh5.

IMPC related publications

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External links

No external links available for Msh5.

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*Msh5^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Msh5^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Msh5^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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