Cdk9 | cyclin dependent kinase 9
Physiological systems
22 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Reproductive system Behavior/neurological Mortality/aging
19 No significant impact
2 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
30Embryo tissues
enlarged epididymis | 1 supporting dataset | Cdk9tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Cdk9tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Cdk9tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
abnormal epididymis morphology | 1 supporting dataset | Cdk9tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
increased vertical activity | 1 supporting dataset | Cdk9tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.9x10-6 | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Cdk9tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * |
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External links
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Cdk9tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Cdk9tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Cdk9tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Cdk9tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |