Smarcb1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Integument Nervous system Mortality/aging
17 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
9Associated diseases
Expression examined in:0Adult tissues
62Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Smarcb1tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Smarcb1tm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
| abnormal coat appearance | 1 supporting dataset | Smarcb1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.05x10-6 | ||
| decreased prepulse inhibition | 4 supporting datasets | Smarcb1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.14x10-6 | ||
| abnormal skin coloration | 1 supporting dataset | Smarcb1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 9.8x10-12 |
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External links
No external links available for Smarcb1.
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| Smarcb1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Smarcb1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Smarcb1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |