Arid3a | AT-rich interaction domain 3A

GeneMGI:1328360Synonyms: Bright, Dri1

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Cardiovascular system Mortality/aging

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

46Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal lens morphology	1 supporting dataset	Arid3a^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	7.99x10^-6
increased circulating insulin level	1 supporting dataset	Arid3a^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.08x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Arid3a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
hemorrhage	1 supporting dataset	Arid3a^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
abnormal limb bud morphology	1 supporting dataset	Arid3a^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
decreased hematocrit	1 supporting dataset	Arid3a^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.1x10^-5
abnormal embryo size	1 supporting dataset	Arid3a^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
decreased erythrocyte cell number	1 supporting dataset	Arid3a^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.98x10^-5
abnormal placenta morphology	1 supporting dataset	Arid3a^{tm1b(KOMP)Wtsi}	homozygote	E15.5	N/A ^*
increased mean corpuscular hemoglobin	1 supporting dataset	Arid3a^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.41x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arid3a.

Associated images

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Histopathology

There is no histopathology data found for Arid3a.

IMPC related publications

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External links

No external links available for Arid3a.

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*Arid3a^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Arid3a^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Arid3a^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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