Rad9a | RAD9 checkpoint clamp component A

GeneMGI:1328356Synonyms: Rad9

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Integument Embryo Growth/size/body region Nervous system Vision/eye Craniofacial Mortality/aging Cardiovascular system

12 No significant impact

4 Not tested

Gene metrics:20Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues

Phenotypes

abnormal vitelline vasculature morphology1 supporting datasetRad9atm1.1(KOMP)WtsihomozygoteE9.5N/A * 
pallor1 supporting datasetRad9atm1.1(KOMP)WtsihomozygoteE9.5N/A * 
abnormal blood vessel morphology1 supporting datasetRad9atm1.1(KOMP)WtsihomozygoteE9.5N/A * 
embryonic growth retardation1 supporting datasetRad9atm1.1(KOMP)WtsihomozygoteE9.5N/A * 
abnormal pharyngeal arch morphology1 supporting datasetRad9atm1.1(KOMP)WtsihomozygoteE9.5N/A * 
abnormal eye anterior chamber depth1 supporting datasetRad9atm1.1(KOMP)WtsiheterozygoteEarly adult2.99x10-5 
abnormal neural tube closure1 supporting datasetRad9atm1.1(KOMP)WtsihomozygoteE9.5N/A * 
abnormal visceral yolk sac morphology1 supporting datasetRad9atm1.1(KOMP)WtsihomozygoteE9.5N/A * 
abnormal chorioallantoic fusion1 supporting datasetRad9atm1.1(KOMP)WtsihomozygoteE9.5N/A * 
abnormal embryo size1 supporting datasetRad9atm1.1(KOMP)WtsihomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rad9atm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse
Rad9atm1.1(KOMP)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Rad9atm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rad9atm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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