Ppp2cb | protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform

GeneMGI:1321161Synonyms: D8Ertd766e, PP2Ac

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Mortality/aging

19 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased cornea thickness	1 supporting dataset	Ppp2cb^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	9.19x10^-5
preweaning lethality, incomplete penetrance	2 supporting datasets	Ppp2cb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased total retina thickness	1 supporting dataset	Ppp2cb^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.31x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ppp2cb.

Associated images

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Histopathology

There is no histopathology data found for Ppp2cb.

IMPC related publications

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External links

No external links available for Ppp2cb.

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*Ppp2cb^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ppp2cb^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ppp2cb^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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