Ptpru | protein tyrosine phosphatase receptor type U

GeneMGI:1321151Synonyms: RPTPlambda, Ptprl

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological

16 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

abnormal sleep behavior4 supporting datasetsPtprutm1.1(KOMP)VlcghomozygoteEarly adult1.84x10-7 
hyperactivity6 supporting datasetsPtprutm1.1(KOMP)VlcghomozygoteEarly adult2.23x10-13 
increased vertical activity1 supporting datasetPtprutm1.1(KOMP)VlcghomozygoteEarly adult9.6x10-6 
persistence of hyaloid vascular system1 supporting datasetPtprutm1.1(KOMP)VlcghomozygoteEarly adult7.47x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ptprutm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Ptprutm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Ptprutm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ptprutm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Ptprutm47213(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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