Sphk1 | sphingosine kinase 1

GeneMGI:1316649Synonyms: SK1, 1110006G24Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Integument Vision/eye Renal/urinary system

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vitreous body morphology	1 supporting dataset	Sphk1^em1(IMPC)Mbp	homozygote	Early adult	7.3x10^-5
small kidney	1 supporting dataset	Sphk1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Sphk1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Sphk1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Sphk1^em1(IMPC)Mbp	homozygote	Early adult	9.23x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sphk1.

Associated images

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Histopathology

There is no histopathology data found for Sphk1.

IMPC related publications

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External links

No external links available for Sphk1.

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*Sphk1^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse
*Sphk1^{tm236205(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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