Chaf1b | chromatin assembly factor 1, subunit B

GeneMGI:1314881Synonyms: CAF-1 subunit B, CAF1A, +6 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating amylase level	1 supporting dataset	Chaf1b^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	7.87x10^-5
increased circulating lipase level	1 supporting dataset	Chaf1b^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.25x10^-6
decreased circulating calcium level	1 supporting dataset	Chaf1b^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.2x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Chaf1b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Chaf1b.

Associated images

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Histopathology

There is no histopathology data found for Chaf1b.

IMPC related publications

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External links

No external links available for Chaf1b.

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*Chaf1b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Chaf1b^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Chaf1b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Chaf1b^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Chaf1b^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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